Prediction of thioguanine-induced cytotoxicity by dual-parameter flow cytometric analysis
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چکیده
منابع مشابه
Synergistic enhancement of 6-thioguanine cytotoxicity by ADP-ribosyltransferase inhibitors.
The effect of the adenosine diphosphoribosyltransferase inhibitors, the substituted benzamides, on the cytotoxicity of 6-thioguanine (6TG) was investigated. Nontoxic concentrations of benzamides potentiated the cytotoxicity of 6TG with a dose enhancement factor of 2, producing a 6-fold increase in cell killing at 10% survival. 6TG treatment did not deplete cellular NAD levels, and in the presen...
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ژورنال
عنوان ژورنال: Cancer Chemotherapy and Pharmacology
سال: 1989
ISSN: 0344-5704,1432-0843
DOI: 10.1007/bf00304760